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Technická 5
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Czech Post certified digital mail code: sp4j9ch

Copyright: UCT Prague 2017
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REPARES (Research Platform on Antibiotic Resistance Spread through Wastewater Treatment Plants), a consortium of leading academic, industry, and policymakers knowledgeable in the Antibiotic Resistance (AR) subject, is geared towards contributing excellence in research on the spread of AR in wastewater treatment plants (WWTPs).

[ikona] => [obrazek] => [ogobrazek] => [pozadi] => [obsah] =>

 ◳ 1 (png) → (ořez 215*215px)

 

The REPARES Team, mostly made up of academic leaders from top universities across Europe, has established strong cooperation with leading European innovators and internationally renowned experts in the water-related antibiotic resistance field.

 

  • UCT will coordinate and work with AR experts to provide methodologies and development of the REPARES platform
  • UCP will leverage its expert leadership in wastewater-mediated antibiotic resistance.
  • TUDelft will deliver methods to apply for international projects successfully.
  • Wetsus will propel cooperation with the non-academic sector.
  • AAU will integrate the REPARES database within the world-accepted MiDAS.
  • UW will do the bioinformatics and the validation of qPCR primers.

 

Background

Antibiotics were developed in 1940 solely for the treatment of infections in humans and animals. Over the years, diseases considered deadly were considered non-issues due to the effectiveness of these medicines. Regrettably, the benefits of antibiotics have been hampered by the development of resistance to antibiotics by bacteria. In recent times certain antibiotics used to eradicate some bacteria have become inactive. Antibiotic resistance (AR) has become prevalent, spreading primarily in populations and the environment. Thus, the development and proliferation of antibiotic resistance are classified among major global threats by the World Health Organization ( ). In addition, the European Centre for Disease Prevention and Control described the colossal effect of AR on the human population resulting in approximately 25,000 deaths per annum, costing the health care sector over  1.5 billion every year.

Proper sanitation of the water cycle is essential to sustain environmental and human health. The role of wastewater treatment plants (WWTPs) and their microbiomes as putative hotspots for the proliferation of antibiotic resistance has questioned how effective these treatment systems are. Increasingly rising public, stakeholders, and governmental perception on this issue has highlighted the need for new quality criteria and installation upgrades.

Despite the gravity of the AR problem, in the wastewater sector, methodological biases have been the sole limiting factor on adequately monitoring the emission, fate, and possible amplification or removal of antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs) across WWTPs. Indeed, there is an urgent need to develop standardized methods and a well-curated database for accurate identification, characterization, and quantification of antibiotic resistance in such complex water matrices as wastewater. These issues are what REPARES aims to solve during the project period.

 ◳ 2 (png) → (ořez 215*215px)REPARES Goals

REPARES aims at advancing the European community’s know-how on antibiotic resistance across sanitation waterways, which in the future will bring society closer to achieving the Sustainable Development Goal of the United Nations. REPARES will act as an important vector to disseminate information on antimicrobial resistance spread within European WWTPs beyond science and technology to reach the academic and non-academic communities utilizing open events, popularization publications, and operation of the REPARES web platform.

Duration of Project

1 October 2019 - 30 September 2022

The relevance of research on antibiotic resistance

  • Antibiotics are one of the common contaminants in wastewater.
  • The increased bacterial antibiotic resistance stems from the spread of antibiotic-resistant bacteria and the transfer of resistance genes.
  • Antibiotic resistance can be acquired through random gene mutations and/or by horizontal gene transfer.
  • The World Health Organization qualified antibiotic resistance development as a significant global threat to society.

REPARES Objectives ◳ Untitled design (jpg) → (originál)

  • The increasing level of UCT’s scientific excellence
  • Improving scientific profiles of UCT’s researchers
  • Increasing UCT’s ability to apply for international projects successfully
  • Fostering cooperation with the non-academic sector
  • Advancing European community’s know-how on antibiotic resistance occurrence and spread in Europe
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Webpage under serious reconstruction! Be back soon!

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Webpage under serious reconstruction! Be back soon!

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Webpage under serious reconstruction! Be back soon!

Newsletter 1 (May 2020)

Newsletter 2 (November 2020)

Newsletter 3 (March 2021)

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What happens with antibiotic leftovers that you put in the garbage? And what about the antibiotics that humans and animals are taking?  

Are there properly treated? Did they disappear without a problem? Not so much. Have a look at our graphics and learn what is the fate of antibiotics in the environment. If you want to know more, have a look at our Antibiotic resistance page.

 ◳ REPARES graphical abstract (jpg) → (originál)

Do you think that when you get rid of bacteria in the toilet, it’s over?

Wrong! You send them to a party to make new friends, share experiences, food, and genetic information. Let's see together what is going on at such a party and how it relates to us. Can antibiotics stop all the bacteria? Certainly not all of them, the unstoppable are called superbugs.

Let's see what are these antibiotic-resistant bacteria and what can we do to avoid them...

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Research platform on antibiotic resistance spread through wastewater treatment plants

 ◳ Bartacek 5 (jpg) → (ořez 215*215px)

 

Jan Bartáček

Project Coordinator, UCT Prague

repares@vscht.cz

 ◳ Pokorna Lucie 6 (jpg) → (ořez 215*215px)

 

Lucie Pokorná

Project Administration, Webmaster

repares@vscht.cz

 ◳ Ojobe Lois (jpg) → (ořez 215*215px)

 

Bukola Lois Ojobe

Webmaster

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REPARES (Research Platform on Antibiotic Resistance Spread through Wastewater Treatment Plants), a consortium of leading academic, industry, and policymakers knowledgeable in the Antibiotic Resistance (AR) subject, is geared towards contributing excellence in research on the spread of AR in wastewater treatment plants (WWTPs).

[ikona] => [obrazek] => [ogobrazek] => [pozadi] => [obsah] =>

 ◳ 1 (png) → (ořez 215*215px)

 

The REPARES Team, mostly made up of academic leaders from top universities across Europe, has established strong cooperation with leading European innovators and internationally renowned experts in the water-related antibiotic resistance field.

 

  • UCT will coordinate and work with AR experts to provide methodologies and development of the REPARES platform
  • UCP will leverage its expert leadership in wastewater-mediated antibiotic resistance.
  • TUDelft will deliver methods to apply for international projects successfully.
  • Wetsus will propel cooperation with the non-academic sector.
  • AAU will integrate the REPARES database within the world-accepted MiDAS.
  • UW will do the bioinformatics and the validation of qPCR primers.

 

Background

Antibiotics were developed in 1940 solely for the treatment of infections in humans and animals. Over the years, diseases considered deadly were considered non-issues due to the effectiveness of these medicines. Regrettably, the benefits of antibiotics have been hampered by the development of resistance to antibiotics by bacteria. In recent times certain antibiotics used to eradicate some bacteria have become inactive. Antibiotic resistance (AR) has become prevalent, spreading primarily in populations and the environment. Thus, the development and proliferation of antibiotic resistance are classified among major global threats by the World Health Organization ( ). In addition, the European Centre for Disease Prevention and Control described the colossal effect of AR on the human population resulting in approximately 25,000 deaths per annum, costing the health care sector over  1.5 billion every year.

Proper sanitation of the water cycle is essential to sustain environmental and human health. The role of wastewater treatment plants (WWTPs) and their microbiomes as putative hotspots for the proliferation of antibiotic resistance has questioned how effective these treatment systems are. Increasingly rising public, stakeholders, and governmental perception on this issue has highlighted the need for new quality criteria and installation upgrades.

Despite the gravity of the AR problem, in the wastewater sector, methodological biases have been the sole limiting factor on adequately monitoring the emission, fate, and possible amplification or removal of antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs) across WWTPs. Indeed, there is an urgent need to develop standardized methods and a well-curated database for accurate identification, characterization, and quantification of antibiotic resistance in such complex water matrices as wastewater. These issues are what REPARES aims to solve during the project period.

 ◳ 2 (png) → (ořez 215*215px)REPARES Goals

REPARES aims at advancing the European community’s know-how on antibiotic resistance across sanitation waterways, which in the future will bring society closer to achieving the Sustainable Development Goal of the United Nations. REPARES will act as an important vector to disseminate information on antimicrobial resistance spread within European WWTPs beyond science and technology to reach the academic and non-academic communities utilizing open events, popularization publications, and operation of the REPARES web platform.

Duration of Project

1 October 2019 - 30 September 2022

The relevance of research on antibiotic resistance

  • Antibiotics are one of the common contaminants in wastewater.
  • The increased bacterial antibiotic resistance stems from the spread of antibiotic-resistant bacteria and the transfer of resistance genes.
  • Antibiotic resistance can be acquired through random gene mutations and/or by horizontal gene transfer.
  • The World Health Organization qualified antibiotic resistance development as a significant global threat to society.

REPARES Objectives ◳ Untitled design (jpg) → (originál)

  • The increasing level of UCT’s scientific excellence
  • Improving scientific profiles of UCT’s researchers
  • Increasing UCT’s ability to apply for international projects successfully
  • Fostering cooperation with the non-academic sector
  • Advancing European community’s know-how on antibiotic resistance occurrence and spread in Europe
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Grant agreement ID:
857552

Start date:
1. October 2019

End date:
30. September 2022

Funded under:
H2020-EU.4.b.

Overal budget:
€ 781 856,25

Coordinated by:
UCT Prague, Czech Republic

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UCT Prague (University of Chemistry and Technology in Prague)

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Jan Bartáček

Project investigator

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Lucie Pokorná

Project administrator

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Sabina Purkrtová

Mobility coordinator

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Kateřina Demnerová

Quality Manager

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Marco Lopez

WP1 leader

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Milada Šolcová

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Stanislav Gajdoš

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Bukola Lois Ojobe

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Dana Vejmelková
(maternity leave)

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TU Delft (Delft University of Technology)

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David Weissbrodt

WP2 leader

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Mark Van Loosdrecht

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David Calderón Franco

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Ben Abbas

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Wetsus (European center of excellence for sustainable water technology)

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Roel Meulepas

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Lucía Hernandez Leal

WP3 leader

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Rebeca Pallares

Heike Schmitt

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UCP (Catholic University of Porto)

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Celia M. Manaia

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Ivone Vaz Moreira

WP4 leader

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Joana Silva

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Jaquelina Rocha

Catarina Fereira

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AAU (Aalborg University)

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Per H. Neilsen

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Marta A. Nierychlo

(maternity leave)

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UW (University of Warszaw)

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Lukasz Dziewit

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Adrian Gorecki

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REPARES (Research Platform in Antibiotic Resistance Spread through Wastewater Treatment Plants), a consortium of leading academic, industry, and policymakers knowledgeable in the Antibiotic Resistance (AR) subject, is geared towards contributing excellence in research on the spread of AR in wastewater treatment plants (WWTPs).

The consortium (mostly made up of academic leaders in the AR field drawn from top universities across Europe) has established strong cooperation with leading European innovators and internationally renowned experts in the water-related AR field.

  • UCT will coordinate and work with AR experts to provide methodologies and development of the REPARES platform.
  • UCP will leverage its expert leadership in wastewater-mediated antibiotic resistance.
  • TUDelft will deliver methods to apply for international projects successfully.
  • Wetsus will propel cooperation with the non-academic sector.
  • AAU will integrate the REPARES database within the world-accepted MiDAS.
  • UW will work on the bioinformatics aspects of AR and the validation of AR detection and quantification.

Background

Antibiotics were developed in 1940 solely for the treatment of infections in humans and animals. Over the years, diseases considered deadly were considered non-issues due to the effectiveness of these medicines. Regrettably, the benefits of antibiotics have been hampered by the development of resistance to antibiotics by bacteria. In recent times certain antibiotics used to eradicate some bacteria have become inactive. Antibiotic resistance (AR) has become prevalent, spreading primarily in populations and the environment. Thus, the development and proliferation of antibiotic resistance are classified among major global threats by the World Health Organization ( ). In addition, the European Centre for Disease Prevention and Control described the colossal effect of AR on the human population resulting in approximately 25,000 deaths per annum, costing the health care sector over  1.5 billion every year.

Proper sanitation of the water cycle is essential to sustain environmental and human health. The role of wastewater treatment plants (WWTPs) and their microbiomes as putative hotspots for the proliferation of antibiotic resistance has questioned how effective these treatment systems are. Increasingly rising public, stakeholders, and governmental perception on this issue has highlighted the need for new quality criteria and installation upgrades.

Despite the gravity of the AR problem, in the wastewater sector, methodological biases have been the sole limiting factor on adequately monitoring the emission, fate, and possible amplification or removal of antibiotic-resistant bacteria (ARB) and antibiotic resistance genes (ARGs) across WWTPs. Indeed, there is an urgent need to develop standardized methods and a well-curated database for accurate identification, characterization, and quantification of antibiotic resistance in such complex water matrices as wastewater. These issues are what REPARES aims to solve during the project period.

  ◳ Repares Icon (png) → (ořez 215*215px)REPARES Goals

REPARES aims at advancing the European community’s know-how on antibiotic resistance across sanitation waterways, which in the future will bring society closer to achieving the Sustainable Development Goal of the United Nations. REPARES will act as an important vector to disseminate information on antimicrobial resistance spread within European WWTPs beyond science and technology to reach the academic and non-academic communities utilizing open events, popularization publications, and operation of the REPARES web platform.

Duration of Project

1 October 2019 - 30 September 2022

The relevance of research on antibiotic resistance

  • Antibiotics are one of the common contaminants in wastewater.
  • The increased bacterial antibiotic resistance results from the spread of antibiotic-resistant bacteria and the transfer of resistance genes.
  • Antibiotic resistance can be acquired through random gene mutations and/or by horizontal gene transfer.
  • The World Health Organization qualified antibiotic resistance development to the major global threats to society.
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Grant agreement ID:
857552

Start date:
1. October 2019

End date:
30. September 2022

Funded under:
H2020-EU.4.b.

Overal budget:
€ 781 856,25

Coordinated by:
UCT Prague, Czech Republic

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REPARES aims to connect researchers, water professionals, microbiologists, policymakers and the general public in the common effort to control the spread of antibiotic resistance through wastewater treatment plants. This mainly concerns the discharge of treated wastewater and the application of sewage sludge to arable land. We aim to deliver relevant information on all aspects of this field.

 ◳ 17 (png) → (originál)General public

If you are interested in the basic information on antibiotic resistance, its origin, related health risks, and ways of spread, please visit our Antibiotic Resistance Basics page. There, you will also see links to other information sources and our video materials and infographics. For deeper information on technology, analytical tools, and legislation, visit our specialized pages.

 ◳ 19 (png) → (originál)Wastewater professionals

We provide information on the general efficiency of WWTPs in the removal of Antibiotic Resistant Bacteria (ARB) and Antibiotic Resistance Genes (ARGs). You can find links to various studies performed around the world, legislation, national strategies, etc. You can also find data about specific analytical tools and techniques and if interested, you may join our inter-laboratory study. Finally, you can join one of our seminars or summer schools.

 ◳ 20 (png) → (originál)Microbiologists

You may be interested in the database of ARGs created by REPARES for the MiDAS field guide, in related metagenomics studies, or the most recent analytical techniques. You are most welcome to join our Inter-laboratory study or join one of our seminars, summer schools, or webinars.

 ◳ 18 (png) → (originál)Policymakers and Public authorities

We provide links to various information sources on national legislation and policies and documents by international authorities such as WHO. Also, you can check scientific studies on ARB/ARGs spread and their impact on the environment and public health. You are also sincerely welcome to some of our seminars, webinars, or summer schools.

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Our colleagues (Ivone Vaz MoreiraJoana Silva, and Célia Manaia) and other exceptional researchers published a well-rounded study on antibiotic resistance in wastewater focusing on Poland and Portugal. The study titled ‘Antibiotic resistance in wastewater, does the context matter? Poland and Portugal, as a case study,’ focused on both countries as areas with high prevalence of antibiotic resistance. They hypothesized and discussed trends based on antibiotic use and the abundance of antibiotic resistance agents in wastewater before and after treatment. For more on this paper please click this link: https://doi.org/10.1080/10643389.2021.2000828

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REPARES Events

Other Events

Coming soon:

15. International Conference on Antibiotic Resistance and Prevention

August 19-20, 2021 in Bangkok, Thailand

5th AMR Conference, novel antimicrobials & AMR Diagnostics

24–26 August 2021, Delivered digitally

Microbial Bioinformatics Hackathon

11-13 October 2021, virtual edition

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August 2021

15. International Conference on Antibiotic Resistance and Prevention

August 19-20, 2021 in Bangkok, Thailand

5th AMR Conference, novel antimicrobials & AMR Diagnostics

24–26 August 2021, Delivered digitally

15. International Conference on Narrow-Spectrum Antibiotics and Antimicrobial Resistance

August 30-31, 2021 in Moscow, Russia

September 2021

-

October 2021

Microbial Bioinformatics Hackathon

11-13 October 2021, virtual edition

15. International Conference on Antimicrobial Plant Extracts, Phytochemicals and Cross-Resistance

October 18-19, 2021 in Dubai, United Arab Emirates

15. International Conference on Environment, Antibiotics and Antibiotic Resistance

October 18-19, 2021 in Dubai, United Arab Emirates

15. International Conference on Antibiotic Resistance and Clinical Bacteriology

October 21-22, 2021 in Athens, Greece

15. International Conference on Antibiotic Resistance and Knowledge on Antimicrobials

October 21-22, 2021 in Athens, Greece

November 2021

World Anti-Microbial Resistance Congress

8-9 November 2021, Washington DC, United States

15. International Conference on Broad-Spectrum Antibiotics and Antimicrobial Resistancehttps://waset.org/broad-spectrum-antibiotics-and-antimicrobial-resistance-conference-in-november-2021-in-rome

November 11-12, 2021 in Rome, Italy

December 2021

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January 2022

16. International Conference on Antibiotic Resistance

January 28-29, 2022 in Sydney, Australia

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Templates REPARES

Logo REPARES

Twinning Coordination Day 2019

Kick-off meeting

Workshop 2 in Porto

 
     

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REPARES Factsheet

Grant agreement ID:
857552

Start date:
1. October 2019

End date:
30. September 2022

Funded under:
H2020-EU.4.b.

Overal budget:
€ 781 856,25

Coordinated by:
UCT Prague, Czech Republic

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